BLS metro-level wage data places Medical Secretaries and Administrative Assistants pay in Winston-Salem, NC at a median of $46,370 per year ($22.29/hr/hour), drawn from the OEWS May 2025 release for this Metropolitan Statistical Area. Compared to the national median of $45,930, Winston-Salem pays +1% above, signaling either concentrated employer demand, a cost-of-living premium, or both. Approximately 3,980 medical secretaries and administrative assistantss are employed across the Winston-Salem MSA in SOC 43-6013.

The Winston-Salem pay distribution spans from $36,560 at the 10th percentile to $54,680 at the 90th — a 1.5× spread that reflects experience tenure, specialization, employer size, and the difference between public-sector, nonprofit, and private-sector compensation inside the metro. The 25th percentile sits at $38,840 and the 75th at $47,310, so half of Winston-Salem-based medical secretaries and administrative assistantss earn within that middle band.

Metro figures capture where you actually work, not just where you live — which matters for commuters. BLS draws metro boundaries from the OMB MSA definitions, so Winston-Salem, NC covers the central city plus outlying counties tied to the metro economically. Remember that OEWS wages reflect base pay only: employer-provided health insurance, retirement matches, stock options, signing bonuses, overtime, and tips are excluded and can add 20-40% to real total compensation. Before using this metro median as a negotiation anchor, triangulate against the same occupation's national profile (linked below), its state-wide NC data, and peer-metro comparisons — a median is a starting point, not a ceiling.