Highest Paying Jobs in Missouri

Top 100 occupations ranked by median annual salary, Bureau of Labor Statistics, May 2025

Highest Salary

$842,800

Orthopedic Surgeons, Except Pediatric

Top 25 Average

$248,846

median salary

$100K+ Jobs

84

occupations

Occupations

100

with wage data

This ranking surfaces the 100 highest-paying occupations in Missouri by BLS OEWS state median salary, drawn from the May 2025 release. At the top, Orthopedic Surgeons, Except Pediatric pays a state median of $842,800, +135% above the national median of $358,550 for the same role. Of the 100 tracked positions, 84 pay above $100,000 per year in Missouri - a useful threshold for separating specialist professional roles from mid-tier employment. The top-10 average sits at $378,344, giving a sense of what elite specialists inside this state actually clear.

The "Difference" column compares each state median to the corresponding national median for the same SOC code, making pay premiums and discounts immediately visible. In this list, 23 of 100 occupations pay above the national median in Missouri, which usually signals one of three things: a local concentration of specialized employers (finance hubs, tech clusters, research universities, federal agencies), a cost-of-living adjustment baked into state-wide wage scales, or scarce in-state talent supply bidding up competitive roles. Occupations paying below the national median are not necessarily bad news, they often reflect lower cost of living in the state or industries where Missouri is not a concentrated employer.

Rankings like this show ceiling-potential by specialty, but they don't tell you the odds of landing one of those roles. Pair this table with the employment column (how many workers the state actually employs in each occupation) and the growth projections on each occupation's national page to see whether the field is expanding or contracting. BLS wages exclude benefits, bonuses, and overtime, especially distorting for top-paying roles where equity and performance compensation can represent 30-50% of total pay. Use this leaderboard to shortlist careers worth exploring in Missouri, then drill into each row's linked profile to check percentile spread, typical education, metro-level variation, and whether projected openings match your timeline.

# Occupation State Median
1 Orthopedic Surgeons, Except Pediatric $842,800
2 Cardiologists $648,070
3 Emergency Medicine Physicians $456,280
4 Orthodontists $332,630
5 Psychiatrists $312,680
6 Physicians, Pathologists $261,830
7 Nurse Anesthetists $242,630
8 Dentists, All Other Specialists $230,130
9 Ophthalmologists, Except Pediatric $228,410
10 Physicians, All Other $227,980
11 Pediatricians, General $223,910
12 General Internal Medicine Physicians $216,570
13 Dentists, General $204,960
14 Athletes and Sports Competitors $172,700
15 Chief Executives $172,320
16 Family Medicine Physicians $171,180
17 Computer and Information Systems Managers $159,460
18 Architectural and Engineering Managers $157,800
19 Financial Managers $143,460
20 Physicists $140,460
21 Pharmacists $137,610
22 Physician Assistants $135,130
23 Psychologists, All Other $134,890
24 Optometrists $133,810
25 Lawyers $133,450
26 Purchasing Managers $132,100
27 Human Resources Managers $130,680
28 Aerospace Engineers $130,680
29 Marketing Managers $130,550
30 Anthropology and Archeology Teachers, Postsecondary $130,500
31 Health Specialties Teachers, Postsecondary $130,490
32 Nurse Midwives $130,220
33 Podiatrists $129,950
34 Nurse Practitioners $129,930
35 Administrative Law Judges, Adjudicators, and Hearing Officers $129,670
36 Medical Dosimetrists $129,610
37 Natural Sciences Managers $129,410
38 Actuaries $129,220
39 Computer and Information Research Scientists $127,820
40 Elevator and Escalator Installers and Repairers $126,750
41 Software Developers $126,120
42 Managers, All Other $125,760
43 Air Traffic Controllers $122,200
44 Electrical Engineers $118,670
45 Industrial Production Managers $117,660
46 Electronics Engineers, Except Computer $117,630
47 Economists $117,010
48 Economics Teachers, Postsecondary $116,530
49 Hydrologists $116,100
50 Sales Managers $115,370
51 Public Relations Managers $114,710
52 Veterinarians $114,660
53 Atmospheric and Space Scientists $114,230
54 Healthcare Diagnosing or Treating Practitioners, All Other $112,260
55 Construction Managers $112,230
56 Fundraising Managers $111,120
57 Database Architects $110,570
58 Training and Development Managers $109,250
59 Compensation and Benefits Managers $106,490
60 Food Scientists and Technologists $105,930
61 Power Distributors and Dispatchers $105,450
62 Nuclear Technicians $104,580
63 Education Administrators, Postsecondary $104,560
64 Medical and Health Services Managers $104,370
65 Computer Hardware Engineers $103,980
66 Web Developers $103,750
67 Information Security Analysts $103,440
68 Computer Network Architects $103,130
69 Commercial Pilots $102,990
70 Engineers, All Other $102,980
71 Transportation, Storage, and Distribution Managers $102,870
72 Medical Scientists, Except Epidemiologists $102,540
73 Chemical Engineers $102,320
74 Atmospheric, Earth, Marine, and Space Sciences Teachers, Postsecondary $102,200
75 Geographers $102,040
76 Power Plant Operators $101,900
77 Computer Occupations, All Other $101,040
78 Art Directors $100,940
79 Financial Risk Specialists $100,620
80 Education Administrators, Kindergarten through Secondary $100,400
81 Facilities Managers $100,380
82 Business Teachers, Postsecondary $100,310
83 Database Administrators $100,270
84 Diagnostic Medical Sonographers $100,130
85 Physics Teachers, Postsecondary $99,970
86 Personal Financial Advisors $99,930
87 Radiation Therapists $99,890
88 Audiologists $99,450
89 Clinical and Counseling Psychologists $99,410
90 Mechanical Engineers $99,330
91 Physical Therapists $99,310
92 Industrial Engineers $99,290
93 Materials Engineers $98,860
94 Social Workers, All Other $98,740
95 Architects, Except Landscape and Naval $98,490
96 Financial and Investment Analysts $98,420
97 Environmental Engineers $98,170
98 Nuclear Medicine Technologists $98,010
99 Airline Pilots, Copilots, and Flight Engineers $97,680
100 Occupational Therapists $97,290

More ways to explore Missouri pay and compare with national data.

About This Data

All salary data comes from the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2025. State-level data reflects wages for workers employed in Missouri. The "Difference" column shows how Missouri pay compares to the national median for that occupation.

Last updated: May 2025. Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025. Rankings by median annual salary in Missouri.

National benchmark comparisons computed against BLS OEWS National Occupational Employment and Wage Estimates, May 2025.

Every figure on WageDex is rendered directly from U.S. Bureau of Labor Statistics wage data, no number is typed in by an editor. These figures are computed directly from BLS OEWS state-level wage data. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 2025.