BLS metro-level wage data places Radiation Therapists pay in Sioux Falls, SD-MN at a median of $86,030 per year ($41.36/hr/hour), drawn from the OEWS May 2025 release for this Metropolitan Statistical Area. Compared to the national median of $105,310, Sioux Falls pays 18% below, which typically tracks with a lower local cost of living or smaller specialized-employer cluster.

The Sioux Falls pay distribution spans from $62,950 at the 10th percentile to $140,490 at the 90th — a 2.2× spread that reflects experience tenure, specialization, employer size, and the difference between public-sector, nonprofit, and private-sector compensation inside the metro. The 25th percentile sits at $80,140 and the 75th at $127,340, so half of Sioux Falls-based radiation therapistss earn within that middle band.

Metro figures capture where you actually work, not just where you live — which matters for commuters. BLS draws metro boundaries from the OMB MSA definitions, so Sioux Falls, SD-MN covers the central city plus outlying counties tied to the metro economically. Remember that OEWS wages reflect base pay only: employer-provided health insurance, retirement matches, stock options, signing bonuses, overtime, and tips are excluded and can add 20-40% to real total compensation. Before using this metro median as a negotiation anchor, triangulate against the same occupation's national profile (linked below), its state-wide SD data, and peer-metro comparisons — a median is a starting point, not a ceiling.