BLS metro-level wage data places Pharmacists pay in Sioux Falls, SD-MN at a median of $148,330 per year ($71.31/hr/hour), drawn from the OEWS May 2025 release for this Metropolitan Statistical Area. Compared to the national median of $140,910, Sioux Falls pays +5% above, signaling either concentrated employer demand, a cost-of-living premium, or both. Approximately 690 pharmacistss are employed across the Sioux Falls MSA in SOC 29-1051.

The Sioux Falls pay distribution spans from $123,700 at the 10th percentile to $174,070 at the 90th — a 1.4× spread that reflects experience tenure, specialization, employer size, and the difference between public-sector, nonprofit, and private-sector compensation inside the metro. The 25th percentile sits at $135,680 and the 75th at $162,770, so half of Sioux Falls-based pharmacistss earn within that middle band.

Metro figures capture where you actually work, not just where you live — which matters for commuters. BLS draws metro boundaries from the OMB MSA definitions, so Sioux Falls, SD-MN covers the central city plus outlying counties tied to the metro economically. Remember that OEWS wages reflect base pay only: employer-provided health insurance, retirement matches, stock options, signing bonuses, overtime, and tips are excluded and can add 20-40% to real total compensation. Before using this metro median as a negotiation anchor, triangulate against the same occupation's national profile (linked below), its state-wide SD data, and peer-metro comparisons — a median is a starting point, not a ceiling.