BLS metro-level wage data places Nurse Practitioners pay in Hilton Head Island-Bluffton-Port Royal, SC at a median of $119,130 per year ($57.28/hr/hour), drawn from the OEWS May 2025 release for this Metropolitan Statistical Area. Compared to the national median of $132,300, Hilton Head Island-Bluffton-Port Royal pays 10% below, which typically tracks with a lower local cost of living or smaller specialized-employer cluster. Approximately 260 nurse practitionerss are employed across the Hilton Head Island-Bluffton-Port Royal MSA in SOC 29-1171.

The Hilton Head Island-Bluffton-Port Royal pay distribution spans from $98,630 at the 10th percentile to $133,150 at the 90th — a 1.3× spread that reflects experience tenure, specialization, employer size, and the difference between public-sector, nonprofit, and private-sector compensation inside the metro. The 25th percentile sits at $102,010 and the 75th at $127,880, so half of Hilton Head Island-Bluffton-Port Royal-based nurse practitionerss earn within that middle band.

Metro figures capture where you actually work, not just where you live — which matters for commuters. BLS draws metro boundaries from the OMB MSA definitions, so Hilton Head Island-Bluffton-Port Royal, SC covers the central city plus outlying counties tied to the metro economically. Remember that OEWS wages reflect base pay only: employer-provided health insurance, retirement matches, stock options, signing bonuses, overtime, and tips are excluded and can add 20-40% to real total compensation. Before using this metro median as a negotiation anchor, triangulate against the same occupation's national profile (linked below), its state-wide SC data, and peer-metro comparisons — a median is a starting point, not a ceiling.