BLS metro-level wage data places Nurse Practitioners pay in Cape Coral-Fort Myers, FL at a median of $129,670 per year ($62.34/hr/hour), drawn from the OEWS May 2025 release for this Metropolitan Statistical Area. Compared to the national median of $132,300, Cape Coral-Fort Myers pays 2% below, which typically tracks with a lower local cost of living or smaller specialized-employer cluster. Approximately 690 nurse practitionerss are employed across the Cape Coral-Fort Myers MSA in SOC 29-1171.

The Cape Coral-Fort Myers pay distribution spans from $104,000 at the 10th percentile to $159,330 at the 90th — a 1.5× spread that reflects experience tenure, specialization, employer size, and the difference between public-sector, nonprofit, and private-sector compensation inside the metro. The 25th percentile sits at $108,790 and the 75th at $132,710, so half of Cape Coral-Fort Myers-based nurse practitionerss earn within that middle band.

Metro figures capture where you actually work, not just where you live — which matters for commuters. BLS draws metro boundaries from the OMB MSA definitions, so Cape Coral-Fort Myers, FL covers the central city plus outlying counties tied to the metro economically. Remember that OEWS wages reflect base pay only: employer-provided health insurance, retirement matches, stock options, signing bonuses, overtime, and tips are excluded and can add 20-40% to real total compensation. Before using this metro median as a negotiation anchor, triangulate against the same occupation's national profile (linked below), its state-wide FL data, and peer-metro comparisons — a median is a starting point, not a ceiling.