BLS metro-level wage data places Biochemists and Biophysicists pay in Buffalo-Cheektowaga, NY at a median of $81,480 per year ($39.17/hr/hour), drawn from the OEWS May 2025 release for this Metropolitan Statistical Area. Compared to the national median of $127,410, Buffalo-Cheektowaga pays 36% below, which typically tracks with a lower local cost of living or smaller specialized-employer cluster. Approximately 80 biochemists and biophysicistss are employed across the Buffalo-Cheektowaga MSA in SOC 19-1021.

The Buffalo-Cheektowaga pay distribution spans from $58,880 at the 10th percentile to $210,520 at the 90th — a 3.6× spread that reflects experience tenure, specialization, employer size, and the difference between public-sector, nonprofit, and private-sector compensation inside the metro. The 25th percentile sits at $66,620 and the 75th at $103,530, so half of Buffalo-Cheektowaga-based biochemists and biophysicistss earn within that middle band.

Metro figures capture where you actually work, not just where you live — which matters for commuters. BLS draws metro boundaries from the OMB MSA definitions, so Buffalo-Cheektowaga, NY covers the central city plus outlying counties tied to the metro economically. Remember that OEWS wages reflect base pay only: employer-provided health insurance, retirement matches, stock options, signing bonuses, overtime, and tips are excluded and can add 20-40% to real total compensation. Before using this metro median as a negotiation anchor, triangulate against the same occupation's national profile (linked below), its state-wide NY data, and peer-metro comparisons — a median is a starting point, not a ceiling.