Highest Paying Jobs in South Carolina

Top 100 occupations ranked by median annual salary, Bureau of Labor Statistics, May 2025

Highest Salary

$359,500

General Internal Medicine Physicians

Top 25 Average

$229,254

median salary

$100K+ Jobs

89

occupations

Occupations

100

with wage data

This ranking surfaces the 100 highest-paying occupations in South Carolina by BLS OEWS state median salary, drawn from the May 2025 release. At the top, General Internal Medicine Physicians pays a state median of $359,500, +40% above the national median of $256,560 for the same role. Of the 100 tracked positions, 89 pay above $100,000 per year in South Carolina - a useful threshold for separating specialist professional roles from mid-tier employment. The top-10 average sits at $295,385, giving a sense of what elite specialists inside this state actually clear.

The "Difference" column compares each state median to the corresponding national median for the same SOC code, making pay premiums and discounts immediately visible. In this list, 32 of 100 occupations pay above the national median in South Carolina, which usually signals one of three things: a local concentration of specialized employers (finance hubs, tech clusters, research universities, federal agencies), a cost-of-living adjustment baked into state-wide wage scales, or scarce in-state talent supply bidding up competitive roles. Occupations paying below the national median are not necessarily bad news, they often reflect lower cost of living in the state or industries where South Carolina is not a concentrated employer.

Rankings like this show ceiling-potential by specialty, but they don't tell you the odds of landing one of those roles. Pair this table with the employment column (how many workers the state actually employs in each occupation) and the growth projections on each occupation's national page to see whether the field is expanding or contracting. BLS wages exclude benefits, bonuses, and overtime, especially distorting for top-paying roles where equity and performance compensation can represent 30-50% of total pay. Use this leaderboard to shortlist careers worth exploring in South Carolina, then drill into each row's linked profile to check percentile spread, typical education, metro-level variation, and whether projected openings match your timeline.

# Occupation State Median
1 General Internal Medicine Physicians $359,500
2 Neurologists $352,680
3 Emergency Medicine Physicians $341,960
4 Orthodontists $311,450
5 Obstetricians and Gynecologists $302,340
6 Physicians, All Other $274,480
7 Nurse Anesthetists $265,480
8 Dermatologists $259,990
9 Dentists, All Other Specialists $246,770
10 Family Medicine Physicians $239,200
11 Anesthesiologists $238,970
12 Psychiatrists $237,250
13 Physicians, Pathologists $236,950
14 Pediatricians, General $217,120
15 Ophthalmologists, Except Pediatric $214,160
16 Radiologists $174,480
17 Life Scientists, All Other $169,440
18 Architectural and Engineering Managers $169,040
19 Chief Executives $168,840
20 Podiatrists $167,110
21 Law Teachers, Postsecondary $162,400
22 Computer and Information Systems Managers $160,860
23 Dentists, General $158,640
24 Advertising and Promotions Managers $156,300
25 Optometrists $145,950
26 Airline Pilots, Copilots, and Flight Engineers $143,580
27 Marketing Managers $143,290
28 Physical Scientists, All Other $141,130
29 Medical Dosimetrists $140,530
30 Physicists $138,400
31 Aerospace Engineers $137,030
32 Marine Engineers and Naval Architects $136,990
33 Psychologists, All Other $136,990
34 Financial Managers $136,160
35 Pharmacists $135,700
36 Computer Network Architects $134,990
37 Purchasing Managers $131,720
38 Natural Sciences Managers $131,140
39 Sales Managers $131,080
40 Database Architects $130,000
41 Managers, All Other $129,960
42 Software Developers $129,450
43 Computer and Information Research Scientists $126,980
44 Industrial Production Managers $126,880
45 Nuclear Engineers $126,570
46 Computer Hardware Engineers $125,110
47 Administrative Services Managers $124,320
48 Human Resources Managers $124,290
49 Nurse Practitioners $123,290
50 Physician Assistants $122,490
51 Nurse Midwives $122,390
52 Veterinarians $122,130
53 Materials Engineers $121,610
54 Lawyers $120,310
55 Training and Development Managers $119,460
56 Nuclear Power Reactor Operators $118,620
57 Sales Engineers $114,250
58 Electronics Engineers, Except Computer $113,720
59 Computer Occupations, All Other $112,260
60 Air Traffic Controllers $112,030
61 Sales Representatives, Wholesale and Manufacturing, Technical and Scientific Products $111,190
62 Engineers, All Other $110,490
63 Biochemists and Biophysicists $109,080
64 Economics Teachers, Postsecondary $109,060
65 Food Scientists and Technologists $108,660
66 Nuclear Technicians $108,490
67 Construction Managers $108,110
68 Transportation, Storage, and Distribution Managers $106,860
69 General and Operations Managers $106,080
70 Information Security Analysts $105,800
71 Commercial Pilots $105,740
72 Medical and Health Services Managers $105,620
73 Public Relations Managers $104,920
74 Mechanical Engineers $104,580
75 Health and Safety Engineers, Except Mining Safety Engineers and Inspectors $104,120
76 Facilities Managers $103,940
77 Engineering Teachers, Postsecondary $103,420
78 Fundraising Managers $103,240
79 Education Administrators, Kindergarten through Secondary $102,440
80 Materials Scientists $101,930
81 Civil Engineers $101,600
82 Chemical Engineers $101,570
83 Architects, Except Landscape and Naval $101,550
84 Physical Therapists $101,330
85 Occupational Therapists $101,130
86 Industrial Engineers $101,060
87 Radiation Therapists $100,790
88 Management Analysts $100,660
89 Social Work Teachers, Postsecondary $100,400
90 Computer Programmers $99,740
91 Compensation and Benefits Managers $99,630
92 Environmental Science Teachers, Postsecondary $99,540
93 Financial Risk Specialists $99,520
94 Bioengineers and Biomedical Engineers $99,130
95 Postmasters and Mail Superintendents $98,940
96 Mining and Geological Engineers, Including Mining Safety Engineers $98,790
97 Electrical Engineers $98,440
98 Computer Systems Analysts $98,280
99 Ship Engineers $97,890
100 Software Quality Assurance Analysts and Testers $97,500

More ways to explore South Carolina pay and compare with national data.

About This Data

All salary data comes from the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2025. State-level data reflects wages for workers employed in South Carolina. The "Difference" column shows how South Carolina pay compares to the national median for that occupation.

Last updated: May 2025. Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025. Rankings by median annual salary in South Carolina.

National benchmark comparisons computed against BLS OEWS National Occupational Employment and Wage Estimates, May 2025.

Every figure on WageDex is rendered directly from U.S. Bureau of Labor Statistics wage data, no number is typed in by an editor. These figures are computed directly from BLS OEWS state-level wage data. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of May 2025.